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  • Title: [Correlation of the bioelectrical activity and energy metabolism in various parts of the dog brain in the process of ontogeny under ether anesthetic conditions].
    Author: Batrak GE, Nerush PA.
    Journal: Farmakol Toksikol; 1975; 38(5):527-31. PubMed ID: 1102328.
    Abstract:
    Experiments conducted on 50 puppies of 2-days, 2-weeks and a month old evidenced that the maturing of the central nervous system in puppies was accompanied by a progressive growth of the bioelectric activity and of the energy exchange forse. With advancing age of the animals the inhibitory action of ether on the oxygen uptake by the tissues of the visual, auditory cortical zones and of the medial thalamus along with the biocurrents in these structures were on a decline. At the same time, as the post-natal development of the animals went on, the processes of oxidative phosphorylation in the cortical segments were disturbed greater than at the 2-week age. In 2-day old animals it did not change substantially by comparison with controls.
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