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  • Title: [Experimental and clinical study of d, 1-oxyphedrin].
    Author: Güller H, Amon I, Lampe I, Paul W, Peters R.
    Journal: Farmakol Toksikol; 1975; 38(5):563-5. PubMed ID: 1102329.
    Abstract:
    Comparative pharmacological and toxicological studies were carried out on animals covering the preparation d,1-oxyphedrine (myophedrine), put out in the GDR, as against the drug 1-oxyphedrine. The activity of both drugs showed no material difference. Clinical trials demonstrated good tolerance of the drug both by healthy persons and patients with its intravenous administration twice a day in amounts of 1 mg, or by mouth--3 times a day in amounts of 8--16 mg. In outpatients with anginal pains after sustained myocardial infarction and also in institutionally treated patients with myocardial infarction the activity of d,1-oxyphedrine proved to be not inferior to that of 1-oxyphedrine.
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