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  • Title: The pharmacological assessment of single drugs and drug combinations in exercise-induced asthma.
    Author: Bierman CW, Pierson WE, Shapiro GG.
    Journal: Pediatrics; 1975 Nov; 56(5 pt-2 suppl):919-22. PubMed ID: 1103075.
    Abstract:
    The relative effectiveness of ephedrine, theophylline, hydroxyzine, and their combinations in relieving cycloergometer exercise-induced asthma were studied in 16 children and adolescents. Ephedrine had no effect on post-exercise asthma, hydroxyzine had weak effect on hastening recovery, while theophylline modified on the post-exercise response significantly. The three drugs together produced an additive effect superior to that of theohylline alone.
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