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  • Title: [Effects of yizhi pills on memory, superoxide dismutase and malondialdehyde of brain and immunity in mice].
    Author: Kou J, Yu Z, Tian J, Ma S, Yan Y.
    Journal: Zhongguo Zhong Yao Za Zhi; 1997 Aug; 22(8):493-6 inside back cover. PubMed ID: 11038919.
    Abstract:
    Passive avoidance tests have shown that Yizhi Pills (YZ) markedly improve the memory of normal mice at a dose of 100 mg/kg after oral administration for fifteen days, and significantly reverse the scopolamine, NaNO2 and EtOH-induced disruptions of memory retention in mice at doses of 100, 200, 500 mg/kg after oral administration for five days. In aged mice induced by D-galactose, YZ also significantly improve the impaired memory, increase the activity of SOD and decrease the content of MDA in brain. All these effects were observed at doses of 200, 500 mg/kg after oral administration for forty-one days. YZ significantly promote blood carbon particle clearance, enhance hemolysin antibody in immunodepressed mice induced by cyclophosphamide, and increase earswelling in immunodepressed mice induced by prednisolonum.
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