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  • Title: Effect of enterocin CRL35 on Listeria monocytogenes cell membrane.
    Author: Minahk CJ, Farías ME, Sesma F, Morero RD.
    Journal: FEMS Microbiol Lett; 2000 Nov 01; 192(1):79-83. PubMed ID: 11040432.
    Abstract:
    The antimicrobial peptide Enterocin CRL35, a class II bacteriocin, produces at high concentrations (8 microg ml(-1)) localized holes in the wall and cellular membrane of Listeria monocytogenes, reflected in the efflux of macromolecules such as proteins and other ultraviolet-absorbing materials. At lower concentrations (0.5 microg ml(-1)), neither ultra structural changes nor macromolecules efflux were observed, however potassium and phosphate ions were released, dissipating the proton motive force. As a result the bacteria were killed.
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