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  • Title: Necrotizing granulomata of the aortic valve in Wegener's disease.
    Author: Bruno P, Le Hello C, Massetti M, Babatasi G, Saloux E, Galateau F, Khayat A.
    Journal: J Heart Valve Dis; 2000 Sep; 9(5):633-5. PubMed ID: 11041176.
    Abstract:
    Wegener's disease is an inflammatory disease of unknown etiology, characterized by a granulomatous-necrotizing general vasculitis. Cardiac involvement in the form of aortic pathology is not frequent. We report a case of Wegener's granulomatosis which required prosthetic aortic valve replacement for aortic valve insufficiency. Microscopic examination of the valve demonstrated histopathology typical of Wegener's disease.
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