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  • Title: A technique for intensifying BCG sensitivity.
    Author: Parmett SR, Klein E.
    Journal: J Med; 1975; 6(3-4):213-6. PubMed ID: 1104733.
    Abstract:
    Sensitization to BCG (Bacille Calmette-Guérin) appears to be more effective when it is carried out at the site of a delayed hypersensitivity challenge reaction to DNCB (1-chloro, 2,4-dinitrobenzene) than when it is carried out at unchallenged sites in non-sensitized animals. The effectiveness of BCG sensitization was determined by measurement of the intensity of the PPD (Purified Protein Derivative of tuberculin) 24-hour skin test. Possible mechanisms for this phenomenon and its implications for cancer immunotherapy are considered.
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