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  • Title: Mater, a maternal effect gene required for early embryonic development in mice.
    Author: Tong ZB, Gold L, Pfeifer KE, Dorward H, Lee E, Bondy CA, Dean J, Nelson LM.
    Journal: Nat Genet; 2000 Nov; 26(3):267-8. PubMed ID: 11062459.
    Abstract:
    Maternal effect genes produce mRNA or proteins that accumulate in the egg during oogenesis. We show here that Mater, a mouse oocyte protein dependent on the maternal genome, is essential for embryonic development beyond the two-cell stage. Females lacking the maternal effect gene Mater are sterile. Null males are fertile.
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