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  • Title: [Adult acute lymphoblastic leukemia presenting a near haploid karyotype].
    Author: Kimura M, Yufu Y, Kawano R, Goto T, Takatsuki H, Uike N.
    Journal: Rinsho Ketsueki; 2000 Sep; 41(9):764-7. PubMed ID: 11070941.
    Abstract:
    Thirty cases of childhood acute lymphoblastic leukemia (ALL) with a near haploid karyotype (< 30 chromosomes) have been reported so far. However, despite a few cases of severely hypodiploid (30-39 chromosomes) ALL, no near haploid cases have been reported in adult patients. Here, we describe a 64-year-old woman with ALL (L2, CD10+ 19+ 34+ HLA-DR+) presenting a near haploid karyotype of 27, X, +X, +6, +10, +21/54, idem x 2. She died of septic shock during complete remission 6.5 months after the diagnosis.
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