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  • Title: Clathculins A and B, two novel nitrogen-containing metabolites from the sponge Clathrina aff. reticulum.
    Author: Rudi A, Schleyer M, Kashman Y.
    Journal: J Nat Prod; 2000 Oct; 63(10):1434-6. PubMed ID: 11076572.
    Abstract:
    Two novel acyclic diaza alkenynes, clathculins A and B (1 and 2), were isolated from the Indo-Pacific sponge Clathrina aff. reticulum collected in Sodwana Bay, South Africa. The structure of the mixture of the two unstable inseparable compounds was established by spectroscopic analysis, mainly 1D and 2D NMR measurements and two chemical transformations. Clathculins A and B are the first reported linear marine metabolites containing a 1,2-diaminoethane moiety.
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