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  • Title: [The neurologic complications of Paget's disease].
    Author: Hubault A, Bourgeois P.
    Journal: Rev Rhum Mal Osteoartic; 1975 Oct; 42(10):563-71. PubMed ID: 1108163.
    Abstract:
    There are several neurological complications of Paget's disease. They may concern the medulla, the cauda equina, and also the cerebral trunk, the cranial nerves, and the brain. Complications are rare when the great frequency of Paget's disease is considered. But they should be recognized because they constitute an aspect of the disease the treatment of which is usually well tolerated of even negligible. The signs of involvement of the medulla, of the cauda equina, and those which complicate the basilar impressions usually develop in a progressive and not very spectacular fashion. Nevertheless, they should be recognized as soon as possible so that therapeutic measures may be taken. The results of modern medical treatments, calcitonin, cellulolytic medications, and possibly others are already sufficiently established to justify their use initially. Indications for surgical treatment appear when a check in medical therapy is observed after three months of treatment.
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