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  • Title: The common cold.
    Author: Van Cauwenberge PB, van Kempen MJ, Bachert C.
    Journal: Acta Otorhinolaryngol Belg; 2000; 54(3):397-401. PubMed ID: 11082776.
    Abstract:
    Upper respiratory tract infections are one of the most common infectious diseases in man and are mainly caused by rhinoviruses. A rhinoviral cold is characterized by a neutrophilic inflammatory reaction with relatively mild symptoms that rather result from the host inflammatory response to the virus than from a direct viral cytotoxic effect. As regulators of chemotaxis, transmigration and activators of inflammatory and immunocompetent cells, cytokines and mediators were shown to play a crucial role in the pathogenesis of a rhinovirus infection.
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