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  • Title: Isolated granulomatous phlebitis: rare cause of ischemic necrosis of the colon: report of a case.
    Author: Martinet O, Reis ED, Joseph JM, Saraga E, Gillet TM.
    Journal: Dis Colon Rectum; 2000 Nov; 43(11):1601-3. PubMed ID: 11089601.
    Abstract:
    Isolated phlebitis of the gastrointestinal tract is rare and potentially life threatening. We report on a patient who developed peritonitis, requiring emergency laparotomy, total colectomy, and ileostomy because of colon necrosis. The specimen displayed multiple ulcerations and erosions. Histology showed a predominantly lymphocytic infiltrate of small-sized and middle-sized veins in the submucosa and subserosa, associated with granulomas and foci of vein wall necrosis. Arteries were spared. No local recurrence or systemic vasculitis developed during a follow-up period of two years. Isolated granulomatous phlebitis seems to be self-limited, and its cause is unknown. Surgical resection of the diseased intestine is usually curative.
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