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Title: Spironolactone in heart failure--a revived role for an old drug. Author: Bradley C. Journal: Intensive Crit Care Nurs; 2000 Dec; 16(6):403-4. PubMed ID: 11091472. Abstract: Spironolactone is an aldosterone antagonist which has been used as a mild potassium-sparing diuretic and in treatment of ascites in liver failure. Recent studies have shown that it has an additive effect to those of ACE inhibitors in heart failure treatment.[Abstract] [Full Text] [Related] [New Search]