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  • Title: Acute renal failure: unusual complication of Epstein-Barr virus-induced infectious mononucleosis.
    Author: Lei PS, Lowichik A, Allen W, Mauch TJ.
    Journal: Clin Infect Dis; 2000 Dec; 31(6):1519-24. PubMed ID: 11096030.
    Abstract:
    A 17-year-old boy with juvenile rheumatoid arthritis presented with jaundice, confusion, hemolytic anemia, thrombocytopenia, and acute renal failure secondary to titer-confirmed acute Epstein-Barr virus (EBV). Renal biopsy specimen revealed interstitial nephritis with an inflammatory infiltrate composed of cytotoxic/suppressor T cells, and interstitial mononuclear cell nuclei expressed EBV encoded RNA-1 (EBER-1) mRNA. Methylprednisolone treatment resulted in rapid improvement.
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