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  • Title: [CVID (common variable immunodeficiency): heterogeneous clinical manifestation of the commonest symptomatic primary immunodeficiency disease].
    Author: Pfluger H, Helbling A, Mordasini C, Pichler WJ.
    Journal: Schweiz Med Wochenschr; 2000 Oct 28; 130(43):1590-9. PubMed ID: 11100512.
    Abstract:
    Common variable immunodeficiency is the most common symptomatic primary immunodeficiency disease. The patients typically present with a long history of respiratory tract infections, sometimes sarcoid-like lesions and in rare cases boils. Heterogeneity of initial clinical manifestations as well as insufficient knowledge of the syndrome often delay the diagnosis. However, early therapy is important to reduce infections and in particular the development of bronchiectasis. Documenting 19 cases, we discuss initial clinical manifestations, some clinical complications, diagnostic procedures and therapeutic management.
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