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  • Title: Development of a protocol to prevent opioid-induced constipation in patients with cancer: a research utilization project.
    Author: Robinson CB, Fritch M, Hullett L, Petersen MA, Sikkema S, Theuninck L, Timmer K.
    Journal: Clin J Oncol Nurs; 2000; 4(2):79-84. PubMed ID: 11107380.
    Abstract:
    Opioids are the major class of analgesics used in the management of moderate to severe cancer pain, and constipation is a common side effect of opioid administration. While monitoring for quality-assurance, nurses found that 95% of patients interviewed on a 28-bed oncology unit of a Midwestern hospital reported constipation as the major side effect of their opioid regimen for pain control. Through the efforts of a nursing research utilization committee, a protocol to prevent opioid-induced constipation in patients with cancer was developed and implemented.
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