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  • Title: Analysis of longitudinal data from twins.
    Author: Huggins RM, Hoang NH, Loesch DZ.
    Journal: Genet Epidemiol; 2000 Dec; 19(4):345-53. PubMed ID: 11108644.
    Abstract:
    Longitudinal data from twin pairs may be used to determine how the genetic effects influencing a quantitative trait change with age. Here a model for mixed longitudinal data of Huggins and Loesch [1998] on unrelated individuals is extended to twin studies. The model is fitted using robust statistical methods and a bootstrap procedure is proposed to estimate the percentiles. The method is applied to longitudinal twin data on body mass index in male and female twin pairs aged 5-18 years.
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