These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Experimental study of hemostimulating properties of the tablet form of recombinant human erythropoetin].
    Author: Dygaĭ AM, Kolokol'tsova TD, Kostina NE, Minakova MIu, Nechaeva EA, Pozhen'ko NS, Sandakhchiev LS, Simanina EV, Khlusov IA.
    Journal: Eksp Klin Farmakol; 2000; 63(5):37-40. PubMed ID: 11109524.
    Abstract:
    Specific biological activity of the domestic preparation of recombinant human erythropoietin (RHEPO) in an original pill form was experimentally studied in vitro and in vivo. Administration of the RHEPO parent substance at a concentration of 0.5 10 U/ml significantly accelerated the growth of erythroid colony-forming cells (CFU-E) in the culture of intact nonadherent myelokaryocytes. The erythropoiesis-stimulating properties of the new RHEPO preparation are comparable with those of the well-known injection preparations. The drug action is related to increasing the erythroid cell content in the bone marrow and the reticulocyte and erythrocyte counts in the peripheral blood.
    [Abstract] [Full Text] [Related] [New Search]