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  • Title: Detection of hypertrophic pulmonary osteoarthropathy of skeletal imaging with 99mTc-labeled diphosphonate.
    Author: Donnelly B, Johnson PM.
    Journal: Radiology; 1975 Feb; 114(2):389-91. PubMed ID: 1111006.
    Abstract:
    In two patients with carcinoma of the lung, abnormal findings on skeletal imaging using 99mTc-diphosphonate correctly suggested the diagnosis of hypertrophic pulmonary osteoarthropathy, which was later confirmed radiographically. A scintigraphic pattern of abnormal tracer localization distinguishes this benign condition of bone from bony metastases.
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