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  • Title: Hepatic undifferentiated (embryonal) sarcoma in an adult: a case report and review of the literature.
    Author: Tokunaga Y, Ryo J, Hoppou T, Kitaoka A, Tokuka A, Osumi K, Tanaka T.
    Journal: Eur J Gastroenterol Hepatol; 2000 Nov; 12(11):1247-51. PubMed ID: 11111784.
    Abstract:
    Undifferentiated (embryonal) sarcoma of the liver (USL) is a rare malignant tumour with a poor prognosis. The absence of specific symptoms, the rapid tumour growth, the normality of the common tumour markers, and the consequential delay in the diagnosis often result in significant enlargement of the tumour. To our knowledge, there have been only 42 reported cases of USL in adults worldwide during the 40 years since the clinicopathological entity of USL was defined. We report here a 27-year-old male with USL who has been treated successfully with surgical resection and adjuvant chemotherapy using ifosfamide, adriamycin and cisplatin. Although the prognosis of the disease remains generally poor, long-term survival has been achieved recently in patients with a combination of surgery and multi-agent chemotherapy.
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