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  • Title: Prolonged prodrome, systemic vasculitis, and deafness in Cogan's syndrome.
    Author: Van Doornum S, McColl G, Walter M, Jennens I, Bhathal P, Wicks IP.
    Journal: Ann Rheum Dis; 2001 Jan; 60(1):69-71. PubMed ID: 11114287.
    Abstract:
    Cogan's syndrome is a rare, multisystem disease which occurs predominantly in children and young adults. It was originally described as the combination of interstitial keratitis and audiovestibular disturbance, but other forms of ocular disease, as well as systemic vasculitis, have since been recognised as part of the syndrome. Diagnosis can be difficult if the various manifestations occur separately, but early recognition is important because prompt treatment may prevent deafness. Two cases are presented here illustrating the features of this disease, and providing histological evidence of systemic vasculitis in both.
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