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  • Title: [The effect of loading liver lysosomes with triton WR 1339 on the development of chronic toxic hepatitis].
    Author: Korolenko TA, Titova VG, Dobrovol'skaia SG, Iakobson GS.
    Journal: Biull Eksp Biol Med; 1975 Jan; 79(1):21-3. PubMed ID: 1111637.
    Abstract:
    Preliminary administration of triton WR 1339 produced a favourable effect on the course of chronic toxic hepatitis. This was expressed in a reduction of necrotic zones, a delay in development of connective tissue and in improvement of the functional capacity of the liver. Lysosomes of the liver of animals subjected to the action of CCl-4 under conditions of preliminary administration of a detergent were more stable to the injurious actions in vitro.
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