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  • Title: [Cytostatic therapy reduces the immune defense. Children treated for leukemia have impaired immunity against measles and rubella].
    Author: Nilsson A, Nordin M, De Milito A, Grillner L, Chiodi F, Björk O.
    Journal: Lakartidningen; 2000 Nov 08; 97(45):5116-8. PubMed ID: 11116890.
    Abstract:
    A study is summarized analyzing the levels of serum antibodies against vaccination antigens in 43 children treated for acute lymphoblastic leukemia. Two different therapeutical regimens were used. All children had been immunized against measles and rubella before being diagnosed with leukemia. Eight of the 24 children treated 1986-1991 lacked protective levels of antibodies against measles; four of the 24 children lacked antibodies against rubella. In the second cohort of children (n = 16) treated from 1992 and onwards, nine lacked protective levels of antibodies against measles, eight lacked antibodies against rubella.
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