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  • Title: Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation.
    Author: Schwartzkroin PA.
    Journal: Brain Res; 1975 Mar 07; 85(3):423-36. PubMed ID: 1111846.
    Abstract:
    Intracellular recordings were made from CA1 pyramidal cells in the hippocampal in vitro slice preparation. Neurons displayed characteristics previously described for the intact preparation including: EPSPs, IPSPs, depolarizing after-potentials, bursting, frequency potentiation, double pulse facilitation, and probably dendritis spiking. Cells could be discharged when orthodromic or antidromic pathways were stimulated, with injection of a depolarizing current pulse, and from iontophoresis of glutamic acid. The apparently normal behavior of the neurons makes the isolated hippocampal slice a promising cortical preparation.
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