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  • Title: Preoperative cytological diagnosis of gastric leiomyosarcoma. A report of three cases.
    Author: Cabre-Fiol V, Vilardeli F, Sala-Cladera E, Mota AP.
    Journal: Gastroenterology; 1975 Mar; 68(3):563-6. PubMed ID: 1112458.
    Abstract:
    Gastric leiomyosarcoma has rarely been diagnosed prior to operation. Three cases are presented in which a cytological diagnosis compatible with leiomyosarcoma could be made preoperatively by exfoliative cytology using a brushing technique under direct vision. Data which favor the diagnosis of leiomyosarcoma are: (1) spindle-shaped cells with malignant looking nuclei; (2) cells with extremely long, fiber-like cytoplasms and hyperchromatic nuclei; (3) large, anaplastic malignant cells. Smears from 3 patients showed a mixture of these different cell types. This cytological presentation is probably unique and diagnostic for leiomyosarcoma.
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