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  • Title: High-performance liquid chromatographic assay of trandolapril in capsules.
    Author: Gumieniczek A, Hopkała H.
    Journal: Acta Pol Pharm; 2000; 57(4):253-5. PubMed ID: 11126611.
    Abstract:
    Rapid, simple and accurate chromatographic (HPLC) method for the determination of trandolapril was elaborated. Samples were chromatographed on a LiChrosorb RP-18 column and the mobile phase was acetonitrile -0.067 M phosphate buffer pH 2.7 (7:3, v/v). The UV detection at 220 nm and benazepril as an internal standard were used. The method was tested for linearity (over the range 4-20 micrograms.ml-1), precision and accuracy and was successfully applied for the quantitative determination of trandolapril in capsules.
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