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  • Title: Can measurements of IGF-1 and IGFBP-3 improve the sensitivity of prostate-cancer screening?
    Author: Wolk A, Andersson SO, Mantzoros CS, Trichopoulos D, Adami HO.
    Journal: Lancet; 2000 Dec 02; 356(9245):1902-3. PubMed ID: 11130391.
    Abstract:
    Further well designed studies are urgently needed to clarify if use of prostate-specific antigen (PSA) as a diagnostic test for prostate cancer can be improved by incorporating measurements of serum insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding-protein 3 (IGFBP-3), and if these measurements might also identify men at higher risk.
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