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  • Title: [Treatment of chronic myeloid leukemia with interferon-alpha].
    Author: Szomor A, Molnár L, Nagy A, Dávid M, Alizadeh H, Kecskés M, Vidra T, Kereskai L, Pajor L, Losonczy H.
    Journal: Orv Hetil; 2000 Nov 26; 141(48):2601-4. PubMed ID: 11141958.
    Abstract:
    The authors have treated 38 patients with chronic phase chronic myeloid leukemia in their single center in the last five years. Conventional chemotherapy provided about 40-50% hematological response, interferon-alpha seems to be more effective, complete hematological remission occurred in 65%. Interphase cytogenetics and fluorescein in situ hybridisation technique was used to measure the cytogenetic response. They observed complete cytogenetic remission in two cases (8%), major response in 11 (39%), minor response in 4 (15%) and minimal response in 4 cases (15%). Interferon-alpha is an effective, well-tolerated medicine in the treatment of chronic myeloid leukemia.
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