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  • Title: Pyrrole analogues of chloramphenicol. I. Synthesis and antibacterial activity of DL-threo-1-(1-methyl-4-nitropyrrole-2-yl)-2-dichloroacetamidopropane-1,3-diol.
    Author: Krajewska D, Dabrowska M, Jakoniuk P, Rózański A.
    Journal: Acta Pol Pharm; 2000; 57(3):213-21. PubMed ID: 11143711.
    Abstract:
    The seven-stage synthesis of a pyrrole analogue of chloramphenicol [IX] was described. The compound exhibits a significant antibacterial activity, over the 12-50% range of the chloramphenicol activity.
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