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  • Title: The oxytocin challenge test in the management of high-risk pregnancies.
    Author: Gaziano EP, Hill DL, Freeman DW.
    Journal: Am J Obstet Gynecol; 1975 Apr 01; 121(7):947-50. PubMed ID: 1115184.
    Abstract:
    Appearance of a repetitive late deceleration pattern following oxytocin-induced uterine contractions in the prepartum patient may indicate fetal compromise, while absence of this finding may reflect fetal well-being. In this study, 72 patients at risk for intrauterine asphyxia underwent 81 satisfactory oxytocin challenge tests. Eight tests in seven patients were interpreted as positive; 72, as negative; and one, as suspicious. In 64 patients with negative tests, no fetal deaths or neonatal asphyxial depressions were observed. One patient developed intrapartum fetal distress with late decelerations 8 days after a negative test and was delivered by cesarean section. The positive test appears to correlate meaningfully with other clinical parameters reflecting intrauterine compromise.
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