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  • Title: Antibiotic resistance patterns of group B streptococcus in antenatal genital cultures.
    Author: Silverman NS, Morgan M, Nichols WS.
    Journal: J Reprod Med; 2000 Dec; 45(12):979-82. PubMed ID: 11153257.
    Abstract:
    OBJECTIVE: To identify the antibiotic susceptibility patterns of group B streptococcus (GBS) isolated from antenatal genital screening cultures. STUDY DESIGN: One hundred thirty-five sequential GBS isolates underwent susceptibility testing by Kirby-Bauer disk diffusion to a variety of commonly used antibiotics. RESULTS: All isolates were susceptible to cefazolin, chloramphenicol and vancomycin. Resistance to clindamycin and erythromycin, the currently recommended alternative antibiotics for intrapartum GBS prophylaxis in penicillin-allergic women, was found in 8.2% and 9.6% of GBS isolates tested, respectively. CONCLUSION: These findings raise concerns regarding the need for both confirmation of a history of penicillin allergy in pregnant women and performance of antibiotic susceptibility testing on GBS isolated in genital screening cultures from penicillin-allergic patients.
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