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  • Title: [Liver function in undisturbed pregnancy].
    Author: Schlebusch H, Schander K, Sorger M, Harnack H.
    Journal: Fortschr Med; 1976 Nov 18; 94(33):1895-9. PubMed ID: 11162.
    Abstract:
    In order to evaluate liver function during pregnancy the enzyme activities of GPT, GOT, GLDH, LDH, AP, LAP, gamma-GT and CHE were determined in 272 healthy pregnant women from the 16th week of gestation up to term. The normal range of GPT, GOT, GLDH, LDH, gamma-GT and CHE did not differ significantly from those in non-pregnant women. Increases in AP and LAP are conditioned by placental synthesis. The functional reserves of a healthy liver obviously suffice to compensate for increased demands during pregnancy. Increases in enzyme aktivities during pregnancy are not physiologic - except for increases in AP and LAP.
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