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  • Title: Spontaneous fluctuations of human placental lactogen during normal pregnancy.
    Author: Vigneri R, Squatrito S, Pezzino V, Cinquerui E, Proto S, Montoneri C.
    Journal: J Clin Endocrinol Metab; 1975 Mar; 40(3):506-9. PubMed ID: 1117057.
    Abstract:
    Six women in the 3rd trimester of normal pregnancy had measurements of circulating placental lactogen (hPL) levels using a continuous blood sampling technique for 10-15 h. In addition, in 3 pregnant women hPL was assayed at 10-min intervals for 60-90 min. Both these procedures showed that hPL serum levels fluctuate irregularly during normal pregnancy. The magnitude and frequency of these fluctuations make the significance of a single hPL determination less reliable as a test of placental function.
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