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  • Title: Leprosy lipid provides the key to Schwann cell entry.
    Author: Young DB.
    Journal: Trends Microbiol; 2001 Feb; 9(2):52-4. PubMed ID: 11173227.
    Abstract:
    A recent study has demonstrated that the species-specific phenolic glycolipid of Mycobacterium leprae triggers uptake into Schwann cells by interaction with laminin-2 and the alpha-dystroglycan receptor. This finding emphasizes the importance of lipids in the biology of mycobacterial infection and suggests possible strategies to combat nerve damage in leprosy.
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