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  • Title: Effect of alpha-retinyl acetate on growth of hamsters fed vitamin A-deficient diets.
    Author: Clamon GH, Sporn MB, Smith JM, Henderson WR.
    Journal: J Nutr; 1975 Feb; 105(2):215-9. PubMed ID: 1117337.
    Abstract:
    The capacity of the alpha-isomer of retinyl acetate to support growth in hamsters fed a vitamin A-deficient diet was assessed over a 40-fold dose range. Although decreased relative potency of the alpha isomer, as compared with the beta isomer, was found, sustained weight gain and survival for 6 months were achieved with a weekly intraperitoneal dose of 300 mug of the alpha isomer. An intraperitoneal dosage of alpha-retinyl acetate resulted in greater activity than an oral dosage.
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