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  • Title: Interleukin 12 and autoimmune diabetes.
    Author: Adorini L.
    Journal: Nat Genet; 2001 Feb; 27(2):131-2. PubMed ID: 11175771.
    Abstract:
    Interleukin 12 (IL-12) has been implicated in the pathogenesis of type 1 diabetes in the non-obese diabetic (NOD) mouse. Following this lead, a new locus associated with human type 1 diabetes, IDDM18, has been identified near the gene encoding the p40 subunit of interleukin 12 (IL12B). This finding has potential implications for the prediction of at-risk individuals and, perhaps, for the implementation of prevention strategies relevant to several autoimmune diseases.
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