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  • Title: Efficacy of ofloxacin and other otic preparations for otitis externa.
    Author: Ruben RJ.
    Journal: Pediatr Infect Dis J; 2001 Jan; 20(1):108-10; discussion 120-2. PubMed ID: 11176588.
    Abstract:
    Ofloxacin otic is as effective in curing otitis externa in children (<12 years of age) as is the preparation combining polymyxin/neomycin plus hydrocortisone and as ciprofloxacin otic. Furthermore ofloxacin otic, as it requires less frequent dosing, is likely to encourage greater patient adherence and consequently to achieve a better cure rate than both of these treatment options. Because a number of cases of otitis externa are complicated by an undiagnosed tympanic membrane perforation, the lack of ototoxicity associated with ofloxacin otic makes it a particularly safe option for use in these patients.
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