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Title: Effect of Semax on homeostasis of gastric mucosa in albino rats. Author: Zhuikova SE, Smirnova EA, Bakaeva ZV, Samonina GE, Ashmarin IP. Journal: Bull Exp Biol Med; 2000 Sep; 130(9):871-3. PubMed ID: 11177268. Abstract: The ACTH(4-7)analogue Semax administered intraperitoneally in a dose of 50 microg/kg 1 h before exposure to ulcerogenic factors (ethanol, water immersion immobilization stress) protected gastric mucosa from damage. Postoperative treatment with Semax for 5 days after application of glacial acetic acid on the mucosa prevented acetic acid-induced ulcers and promoted their healing. The antiulcer effects of Semax in the studied dose were comparable with those of tripeptide Pro-Gly-Pro in a dose of 1 mg/kg.[Abstract] [Full Text] [Related] [New Search]