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  • Title: Novel treatment of meningitis caused by multidrug-resistant Mycobacterium tuberculosis with intrathecal levofloxacin and amikacin: case report.
    Author: Berning SE, Cherry TA, Iseman MD.
    Journal: Clin Infect Dis; 2001 Feb 15; 32(4):643-6. PubMed ID: 11181130.
    Abstract:
    We report the case of a 25-year-old HIV-negative man with disseminated multidrug-resistant tuberculosis (MDRTB), who-on a retreatment regimen-experienced total resolution of TB miliary disease, but progressive TB meningitis. Therefore, intrathecal treatment with amikacin and levofloxacin was instituted, with successful clinical and microbiological results.
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