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  • Title: Pathomorphological characteristics of experimental toxemia induced by thermostable Yersinia pseudotuberculosis toxin.
    Author: Isachkova LM, Timchenko NF, Nedashkovskaya EP, Raznik SD.
    Journal: Bull Exp Biol Med; 2000 Nov; 130(11):1123-6. PubMed ID: 11182834.
    Abstract:
    Pathogenic properties of thermostable toxin responsible for pathogenicity of Yersinia pseudotuberculosis were experimentally studied. The toxin exerted a pronounced polyorgan cytopathogenic effect with predominating degenerative destructive changes and membranolytic effect on cell ultrastructure of parenchymatous organs. The toxin is believed to be directly involved in the development of typical pathomorphological picture of pseudotuberculosis, which confirms its pathogenetic role.
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