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  • Title: The spleen as a hematological organ.
    Author: Spencer RP, Pearson HA.
    Journal: Semin Nucl Med; 1975 Jan; 5(1):95-102. PubMed ID: 1118737.
    Abstract:
    The spleen has multiple roles in human physiology. Eitht major functions are discussed in this review (hematopoiesis, erythrocyte destruction, hormonal function in hematopoiesis, culling and pitting, platelet and leukocyte destruction, particulate removal, reservoir function, and immunologic function). Splenic trapping of red cells, and the concepts of hypersplenism, are major responsibilities of this organ. These aspects are placed in perspective for the reader.
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