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  • Title: The management of organophosphate intoxication.
    Author: Worrell CL.
    Journal: South Med J; 1975 Mar; 68(3):335-9. PubMed ID: 1118773.
    Abstract:
    This review attempts to reiterate the problem of organophosphate intoxication and the pathophysiologic problems created by these compounds. A discussion of management is included. The case reported of a two-year old child serves to illustrate the tremendously high doses of atropine which may be required to block the acetylcholine accumulated at cholinergic synapses as a result of phosphorylation of acetylcholinesterase by organophosphorus compounds.
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