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Title: [The role of L-3-I-123-iodine-alpha-methyltyrosine SPECT in cerebral gliomas]. Author: Weckesser M, Schmidt D, Matheja P, Coenen HH, Langen KJ. Journal: Nuklearmedizin; 2000 Dec; 39(8):233-40. PubMed ID: 11189900. Abstract: L-3-I-123-iodine-alpha-methyltyrosine (IMT) is a I-123-labelled amino acid which has been used for single photon emission computed tomography (SPECT) of cerebral gliomas for more than a decade. IMT-SPECT is able to detect tumor infiltration independent of disruptions of the blood-brain barrier which is often difficult with computed tomography or magnetic resonance tomography. The method is useful to detect tumor recurrences and helps to distinguish gliomas from non-neoplastic brain masses. IMT-SPECT is thus a valuable tool in the diagnostic evaluation and in therapy planning of patients with cerebral gliomas.[Abstract] [Full Text] [Related] [New Search]