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  • Title: Gastric MALT lymphoma. A clinico-pathological study of 65 cases. Relationship to Helicobacter pylori.
    Author: Ben Rejeb A, Kchir N, Bouali MR, Ebdelli N, Fsili R, Khediri F, Ben Ayedó F, Zitouna MM, Ben Mami N, Kacem M, Filali A, Ben Ammar A.
    Journal: Tunis Med; 2000; 78(8-9):484-93. PubMed ID: 11190724.
    Abstract:
    We report 65 cases of MALT gastric lymphomas. HP was looked for with Giemsa and Whartin Starry stains. Immunohistochemistry was done with PAP method. Anti-HP treatment was used in 9 cases. 38 were of low grade of malignancy, 23 were high grade, 4 were high grade with a low grade component. The mean age was 51.5 years, the sex ratio 1.5. Epigastric pain was the most frequent feature (87.7% of cases). Endoscopically, low grade lymphomas presented as unique or multiple ulcerations (55.3% of cases) with antral localisation (52.6% of cases). 60% of our patients were stage IE, of which 61% had low grade lymphoma, 18% were at stage II2E, 10% at stage III and 10% at stage IV. From 23 operated patients, 29% had early lymphoma which was low grade malignant in 71.5% of cases, and 71% had lymphomas which were widely spread beyond the submucosa. HP was found in 63% of cases. Histologic regression of two early lymphomas of low grade malignancy was achieved after HP eradication.
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