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  • Title: [Dangerous hyperkalemia as sequelae of new treatment strategies of heart failure].
    Author: Fuster D, Frey FJ, Ferrari P.
    Journal: Praxis (Bern 1994); 2000 Dec 07; 89(49):2073-6. PubMed ID: 11190849.
    Abstract:
    This case report presents a patient who developed severe life-threatening hyperkalemia following combined treatment with an ACE-inhibitor and the aldosterone-antagonist spironolactone for his congestive heart failure and who also suffered from pre-existing moderate renal failure. The pathophysiological reasons and the clinical evidence for the treatment of congestive heart failure with a combination of ACE-inhibitors and aldosterone-antagonists are discussed in details. The reasons for the occurrence of hyperkalemia in this patient and how spironolactone should be prescribed in patients with congestive heart failure are also elucidated.
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