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  • Title: [Drugs or enuresis alarm can help more children stay dry at night. To wet oneself is distressing and taxing for self-confidence].
    Author: Bengtsson B, Wassén C.
    Journal: Lakartidningen; 2000 Nov 22; 97(47):5459-61. PubMed ID: 11192770.
    Abstract:
    Monosymptomatic primary nocturnal enuresis (PNE) is commonly treated with desmopressin (Minirin), resulting in dry nights for approximately 70-85 percent of affected children. However, nocturnal enuresis is sometimes accompanied by signs of bladder dysfunction. A history of urgency, frequency, daytime wetting or urinary tract infection may indicate the presence of a hyperactive, unstable bladder. In these cases, desmopressin in combination with an anticholinergic drug (i.e. oxybutynin; Ditropan) given at bedtime, or desmopressin and a bed alarm, will increase the number of patients with dry nights. This therapy can now be offered not only by pediatricians but also by general practitioners.
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