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  • Title: Binding of thiostrepton to a complex of 23-S rRNA with ribosomal protein L11.
    Author: Thompson J, Cundliffe E, Stark M.
    Journal: Eur J Biochem; 1979 Jul; 98(1):261-5. PubMed ID: 111931.
    Abstract:
    Thiostrepton binds with high affinity and with a 1 : 1 stoichiometry to a complex formed between Escherichia coli 23-S ribosomal RNA and ribosomal protein L11 of E. coli or the homologous protein BM-L11 of Bacillus megaterium. In the presence of T1 ribonuclease, protein BM-L11 and thiostrepton protect from degradation a fragment of E. coli 23-S RNA estimated to be about 50 nucleotides in length.
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