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  • Title: [Histological and immunohistochemical characteristics of diffuse large cell B-cell lymphomas].
    Author: Krivolapov IuA, Saltykova LB, Kozlova AA.
    Journal: Arkh Patol; 2000; 62(6):19-24. PubMed ID: 11198116.
    Abstract:
    In the REAL classification, diffuse large B-cell non-Hodgkin's lymphomas are grouped together. We investigated histological variants and immunohistochemical profile of diffuse large B-cell lymphomas in 53 patients. Accuracy of the diagnosis was 73.6% without immunohistochemistry. The usefulness of immunophenotyping in making the correct diagnosis depended on a specific histological variant of diffuse large B-cell lymphoma. Variants with polymorphic and anaplastic morphology or massive reactive component have been diagnosed by routine histological methods with poor validity.
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