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  • Title: [Sarcoidosis with a prevalent splenic localization: surgical option (presentation of a case].
    Author: Benfatto GP, Benfatto SA, Licari V, Cirnigliaro G, Giovinetto A.
    Journal: Chir Ital; 2000; 52(6):713-7. PubMed ID: 11200009.
    Abstract:
    Sarcoidosis is a granulomatosis disease of unknown origin with a variable clinical presentation. The reported frequency of splenomegaly in sarcoidosis ranges from 1% to 40%. Splenomegaly has been associated with clinical evidence of more extensive thoracic and extrathoracic sarcoidosis. We describe an interesting case of sarcoidosis with giant splenomegaly and abdominal pain but no evidence of systemic involvement. Sarcoidosis must be considered in the differential diagnosis of splenomegaly. The main indication for splenectomy is splenomegaly with resulting discomfort and/or haematological abnormalities. Though the natural history of sarcoidosis is generally unchanged after splenectomy, in our patient the operation resolved the abdominal pain completely with no need for further therapy.
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